Form 424B3 Astra Space, Inc.

Submitted under rule (424)(b)(3)

registration No. 333-267113


(to the prospectus of September 13, 2022)



34,000,000 CLASS A SHARES

This prospectus supplement amends and supplements the prospectus dated 13 September 2022 (as amended or amended, the “Prospectus”), which forms part of our registration statement on
Form S-1 (#333-267113). This Prospectus supplement is filed to update the information in the prospectus to supplement the information contained in our most recent report Form 8-K, filed with the Securities and Exchange Commission on September 21, 2022 (the “Current report“). Accordingly, we have included the current report in this prospectus supplement.

The prospectus and this prospectus supplement relate to the offering and resale of up to 34,000,000 Class A common shares with a par value of $0.0001 per share (the “class A common stock“) of Astra Space, Inc. through B. Riley Principal Capital II, LLC (the “sell shareholder“). The shares contained in the prospectus and this prospectus consist of Class A common stock which we may, at our discretion, issue and sell to the selling shareholder pursuant to a common stock purchase agreement we entered into with the selling shareholder on August 2, 2022 (the “Purchase contract“). These Class A Common Shares will include (i) up to 33,281,805 shares of our Class A Common Shares which we may, in our sole discretion, sell to the selling shareholder from time to time after the date of this Prospectus pursuant to the Purchase Agreement and (ii) 718,195 shares of our Class A common stock, each of which we have issued or may issue to the selling shareholder upon the satisfaction of certain conditions in consideration for its obligation to purchase shares of our class A common stock for one or more purchases to which we make them may instruct in our sole discretion from time to time after the date of this Prospectus pursuant to the Purchase Agreement. See “The committed equity financing‘ for a description of the contract of sale and ‘sell shareholder” for more information about the selling shareholder.

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Our Class A common stock is listed on the Nasdaq under the symbol “ASTR.” On September 20, 2022, the closing price of our Class A common stock was $0.72 per share.

This prospectus supplement updates and supplements the information in the prospectus and is not complete without the prospectus, including any amendments or supplements, and may only be delivered or used in combination with it. This Supplement should be read in conjunction with the Prospectus and if there is any inconsistency between the information in the Prospectus and this Supplement, you should rely on the information in this Supplement.

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Investing in our securities involves risks that are described in “Risk Factors” Section beginning on page 17 of the Prospectus.

Neither the SEC nor any state securities commission has approved or disapproved the securities to be issued pursuant to the prospectus or determined whether the prospectus or this prospectus supplement is accurate or complete. Any representation to the contrary is punishable.

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The date of this Prospectus Supplement is 21 September 2022.

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